{"id":1903,"date":"2025-10-27T10:49:02","date_gmt":"2025-10-27T10:49:02","guid":{"rendered":"https:\/\/studenthub.elsevier.com\/es\/?p=1903"},"modified":"2025-10-24T11:23:51","modified_gmt":"2025-10-24T11:23:51","slug":"guyton-fisiologia-hemostasia-coagulacion-sanguinea","status":"publish","type":"post","link":"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/","title":{"rendered":"Hemostasia y mecanismos de la coagulaci\u00f3n sangu\u00ednea"},"content":{"rendered":"\n<p>&nbsp;\u00bfSab\u00edas que la hemostasia es nuestro mecanismo natural para prevenir la p\u00e9rdida de sangre? Cuando se rompe un vaso, nuestro cuerpo activa varios procesos: vasoconstricci\u00f3n, formaci\u00f3n de tap\u00f3n de plaquetas, coagulaci\u00f3n y cierre definitivo del agujero.<\/p>\n\n\n\n<p>Para entender estos procesos complejos de forma clara y sencilla, hemos creado unos visuales inspirados en la \u00faltima edici\u00f3n del <strong><em>Tratado de Fisiolog\u00eda M\u00e9dica de Guyton &amp; Hall<\/em><\/strong>. Con m\u00e1s de 1 200 ilustraciones a todo color, cuadros de correlaci\u00f3n cl\u00ednica y cap\u00edtulos cortos, es la herramienta perfecta para dominar la fisiolog\u00eda, especialmente en temas tan fundamentales como la hemostasia.<\/p>\n\n\n\n<p>El t\u00e9rmino\u00a0<em>hemostasia<\/em>\u00a0significa <strong>prevenci\u00f3n de la p\u00e9rdida de sangre<\/strong>. Siempre que se corta o se rompe un vaso, se llega a la hemostasia por varios mecanismos:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>1) la vasoconstricci\u00f3n<\/li>\n\n\n\n<li>2) la formaci\u00f3n de un tap\u00f3n de plaquetas<\/li>\n\n\n\n<li>3) la formaci\u00f3n de un co\u00e1gulo sangu\u00edneo como resultado de la coagulaci\u00f3n sangu\u00ednea<\/li>\n\n\n\n<li>4) la proliferaci\u00f3n final de tejido fibroso en el co\u00e1gulo sangu\u00edneo para cerrar el agujero en el vaso de manera permanente.<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" height=\"1024\" width=\"1024\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/34_e62b72.png?w=1024\" alt=\"\" class=\"wp-image-1905\" srcset=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/34_e62b72.png 1080w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/34_e62b72.png?resize=150,150 150w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/34_e62b72.png?resize=300,300 300w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/34_e62b72.png?resize=768,768 768w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/34_e62b72.png?resize=1024,1024 1024w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/34_e62b72.png?resize=120,120 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" height=\"1024\" width=\"1024\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/35_4d69f1.png?w=1024\" alt=\"\" class=\"wp-image-1906\" srcset=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/35_4d69f1.png 1080w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/35_4d69f1.png?resize=150,150 150w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/35_4d69f1.png?resize=300,300 300w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/35_4d69f1.png?resize=768,768 768w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/35_4d69f1.png?resize=1024,1024 1024w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/35_4d69f1.png?resize=120,120 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" height=\"1024\" width=\"1024\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/36_254427.png?w=1024\" alt=\"\" class=\"wp-image-1907\" srcset=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/36_254427.png 1080w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/36_254427.png?resize=150,150 150w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/36_254427.png?resize=300,300 300w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/36_254427.png?resize=768,768 768w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/36_254427.png?resize=1024,1024 1024w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/36_254427.png?resize=120,120 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" height=\"1024\" width=\"1024\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/37_e3aa46.png?w=1024\" alt=\"\" class=\"wp-image-1909\" srcset=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/37_e3aa46.png 1080w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/37_e3aa46.png?resize=150,150 150w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/37_e3aa46.png?resize=300,300 300w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/37_e3aa46.png?resize=768,768 768w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/37_e3aa46.png?resize=1024,1024 1024w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/37_e3aa46.png?resize=120,120 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Mecanismo de la coagulaci\u00f3n de&nbsp;la sangre<\/h4>\n\n\n\n<p>En la sangre y en los tejidos se han encontrado m\u00e1s de 50 sustancias importantes que causan o afectan a la coagulaci\u00f3n sangu\u00ednea: unas que estimulan la coagulaci\u00f3n, llamadas&nbsp;<em>procoagulantes,<\/em>&nbsp;y otras que inhiben la coagulaci\u00f3n, llamadas&nbsp;<em>anticoagulantes.<\/em>&nbsp;El que la sangre se coagule o no depende del equilibrio entre estos dos grupos de sustancias. En el torrente sangu\u00edneo predominan generalmente los anticoagulantes, por lo que la sangre no se coagula mientras est\u00e1 en circulaci\u00f3n en los vasos sangu\u00edneos. Sin embargo, cuando se rompe un vaso, se activan los procoagulantes de la zona del tejido da\u00f1ado y anulan a los anticoagulantes, y as\u00ed aparece el co\u00e1gulo.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" height=\"1024\" width=\"1024\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/38.png?w=1024\" alt=\"\" class=\"wp-image-1912\" srcset=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/38.png 1080w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/38.png?resize=150,150 150w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/38.png?resize=300,300 300w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/38.png?resize=768,768 768w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/38.png?resize=1024,1024 1024w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/38.png?resize=120,120 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" height=\"1024\" width=\"1024\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/39.png?w=1024\" alt=\"\" class=\"wp-image-1913\" srcset=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/39.png 1080w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/39.png?resize=150,150 150w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/39.png?resize=300,300 300w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/39.png?resize=768,768 768w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/39.png?resize=1024,1024 1024w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/39.png?resize=120,120 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" height=\"1024\" width=\"1024\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/40.png?w=1024\" alt=\"\" class=\"wp-image-1914\" srcset=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/40.png 1080w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/40.png?resize=150,150 150w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/40.png?resize=300,300 300w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/40.png?resize=768,768 768w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/40.png?resize=1024,1024 1024w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/40.png?resize=120,120 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" height=\"1024\" width=\"1024\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/41.png?w=1024\" alt=\"\" class=\"wp-image-1915\" srcset=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/41.png 1080w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/41.png?resize=150,150 150w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/41.png?resize=300,300 300w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/41.png?resize=768,768 768w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/41.png?resize=1024,1024 1024w, https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/41.png?resize=120,120 120w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<ul class=\"wp-block-list\">\n<li><\/li>\n<\/ul>\n\n\n\n<p>El taponamiento tiene lugar en tres etapas esenciales:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>1.\u00a0En respuesta a la rotura del vaso o una lesi\u00f3n de la propia sangre, tiene lugar una cascada compleja de reacciones qu\u00edmicas en la sangre que afecta a m\u00e1s de 12 factores de la coagulaci\u00f3n sangu\u00ednea. El resultado neto es la formaci\u00f3n de un complejo de sustancias activadas llamadas en grupo\u00a0<em>activador de la protrombina.<\/em><\/li>\n\n\n\n<li>2.\u00a0El activador de la protrombina cataliza la conversi\u00f3n de protrombina en trombina.<\/li>\n\n\n\n<li>3.\u00a0La trombina act\u00faa como una enzima para convertir el fibrin\u00f3geno en fibras de fibrina que atrapan en su red plaquetas, c\u00e9lulas sangu\u00edneas y plasma para formar el co\u00e1gulo.<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-cf9dd0f5 wp-block-columns-is-layout-flex\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-column has-background is-layout-flow wp-block-column-is-layout-flow\" style=\"border-radius:28px;background-color:#eee7d7\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20);flex-basis:33.33%\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"155\" height=\"200\" src=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/image_c4d470.png\" alt=\"\" class=\"wp-image-1918\" style=\"width:149px;height:auto\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20);flex-basis:66.66%\">\n<p>Contenido adaptado de <em><strong>Guyton y Hall. Tratado de Fisiolog\u00eda M\u00e9dica<\/strong><\/em>, 14\u00aa edici\u00f3n.<\/p>\n\n\n\n<p>Disponible en formato impreso, eBook y en <a href=\"https:\/\/www.clinicalkey.com\/student\/content\/toc\/3-s2.0-C20200037060\" target=\"_blank\" rel=\"noreferrer noopener\">ClinicalKey Student<\/a>.<\/p>\n\n\n\n<p>Cons\u00edguela en tu librer\u00eda m\u00e1s cercana<a href=\"https:\/\/www.elsevier.com\/es-es\/promotions\/mapa-de-librerias\" rel=\"noreferrer noopener\" target=\"_blank\"> aqu\u00ed.<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp;\u00bfSab\u00edas que la hemostasia es nuestro mecanismo natural para prevenir la p\u00e9rdida de sangre? Cuando se rompe un vaso, nuestro cuerpo activa varios procesos: vasoconstricci\u00f3n, formaci\u00f3n de tap\u00f3n de plaquetas, coagulaci\u00f3n y cierre definitivo del agujero. Para entender estos procesos complejos de forma clara y sencilla, hemos creado unos visuales inspirados en la \u00faltima edici\u00f3n [&hellip;]<\/p>\n","protected":false},"author":164,"featured_media":1921,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[4,56,55],"tags":[],"class_list":["post-1903","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-enfermeria","category-medicina"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hemostasia y coagulaci\u00f3n sangu\u00ednea<\/title>\n<meta name=\"description\" content=\"Apuntes y visuales que repasa en profundidad este proceso, con contenido original de la obra de referencia en fisiolog\u00eda: &#039;Guyton&amp;Halll&#039;.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hemostasia y coagulaci\u00f3n sangu\u00ednea\" \/>\n<meta property=\"og:description\" content=\"Apuntes y visuales que repasa en profundidad este proceso, con contenido original de la obra de referencia en fisiolog\u00eda: &#039;Guyton&amp;Halll&#039;.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/\" \/>\n<meta property=\"og:site_name\" content=\"Student Hub Spain\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-27T10:49:02+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-10-24T11:23:51+00:00\" \/>\n<meta name=\"author\" content=\"jrubio\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/Copy-orange-shape-pattern-from-this-image-3.png\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"jrubio\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/\",\"url\":\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/\",\"name\":\"Hemostasia y coagulaci\u00f3n sangu\u00ednea\",\"isPartOf\":{\"@id\":\"https:\/\/studenthub.elsevier.com\/es\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/Copy-orange-shape-pattern-from-this-image-3.png\",\"datePublished\":\"2025-10-27T10:49:02+00:00\",\"dateModified\":\"2025-10-24T11:23:51+00:00\",\"author\":{\"@id\":\"https:\/\/studenthub.elsevier.com\/es\/#\/schema\/person\/c621f5c2eaaa07591b097e5355bf585f\"},\"description\":\"Apuntes y visuales que repasa en profundidad este proceso, con contenido original de la obra de referencia en fisiolog\u00eda: 'Guyton&Halll'.\",\"breadcrumb\":{\"@id\":\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/studenthub.elsevier.com\/es\/blog\/guyton-fisiologia-hemostasia-coagulacion-sanguinea\/#primaryimage\",\"url\":\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/Copy-orange-shape-pattern-from-this-image-3.png\",\"contentUrl\":\"https:\/\/studenthub.elsevier.com\/es\/wp-content\/uploads\/sites\/11\/2025\/10\/Copy-orange-shape-pattern-from-this-image-3.png\",\"width\":1920,\"height\":1080,\"caption\":\"Hemostasia y coagulaci\u00f3n sangu\u00ednea - Guyton y Hall. 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